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'''Aldosterone''', also called  '''(11ß)-11,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-al''',  is a [[steroid]] [[hormone]].  It is the major [[mineralcorticoid]] and it therefore controls [[electrolyte]] levels, [[blood pressure]] and hydration.  Aldosterone is synthesized from [[corticosterone]] by oxidation of the C-18 methyl group to form an aldehyde.
'''Aldosterone''', also called  '''(11ß)-11,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-al''',  is a [[steroid]] [[hormone]].  It is the major [[mineralcorticoid]] and it therefore controls [[electrolyte]] levels, [[blood pressure]] and hydration.  Aldosterone is synthesized from [[corticosterone]] by oxidation of the C-18 methyl group to form an aldehyde.


Primary aldosteronism underlies about 10% of cases of resistant [[hypertension]].<ref name="pmid18539224">{{cite journal |author=Douma S, Petidis K, Doumas M, ''et al'' |title=Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study |journal=Lancet |volume=371 |issue=9628 |pages=1921–6 |year=2008 |month=June |pmid=18539224 |doi=10.1016/S0140-6736(08)60834-X |url=http://linkinghub.elsevier.com/retrieve/pii/S0140-6736(08)60834-X |issn=}}</ref>
==Primary aldosteronism==
[[Primary aldosteronism]] underlies about 10% of cases of resistant [[hypertension]].<ref name="pmid18539224">{{cite journal |author=Douma S, Petidis K, Doumas M, ''et al'' |title=Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study |journal=Lancet |volume=371 |issue=9628 |pages=1921–6 |year=2008 |month=June |pmid=18539224 |doi=10.1016/S0140-6736(08)60834-X |url=http://linkinghub.elsevier.com/retrieve/pii/S0140-6736(08)60834-X |issn=}}</ref>
 
[[Clinical practice guideline]]s are available for managing primary aldosteronism.<ref name="pmid18552288">{{cite journal| author=Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M et al.| title=Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. | journal=J Clin Endocrinol Metab | year= 2008 | volume= 93 | issue= 9 | pages= 3266-81 | pmid=18552288 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18552288 | doi=10.1210/jc.2008-0104 }} </ref>


==References==
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Aldosterone, a mineralcorticoid steroid.

Aldosterone, also called (11ß)-11,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-al, is a steroid hormone. It is the major mineralcorticoid and it therefore controls electrolyte levels, blood pressure and hydration. Aldosterone is synthesized from corticosterone by oxidation of the C-18 methyl group to form an aldehyde.

Primary aldosteronism

Primary aldosteronism underlies about 10% of cases of resistant hypertension.[1]

Clinical practice guidelines are available for managing primary aldosteronism.[2]

References