Aldosterone: Difference between revisions
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[[Image:Aldosterone DEVolk.jpg|right|thumb|350px|{{#ifexist:Template:Aldosterone DEVolk.jpg/credit|{{Aldosterone DEVolk.jpg/credit}}<br/>|}}Aldosterone, a [[mineralcorticoid]] [[steroid]].]] | [[Image:Aldosterone DEVolk.jpg|right|thumb|350px|{{#ifexist:Template:Aldosterone DEVolk.jpg/credit|{{Aldosterone DEVolk.jpg/credit}}<br/>|}}Aldosterone, a [[mineralcorticoid]] [[steroid]].]] | ||
'''Aldosterone''', also called '''(11ß)-11,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-al''', is a [[steroid]] [[hormone]]. It is the major [[mineralcorticoid]] and it therefore controls [[electrolyte]] levels, [[blood pressure]] and hydration. Aldosterone is synthesized from [[corticosterone]] by oxidation of the C-18 methyl group to form an aldehyde. | '''Aldosterone''', also called '''(11ß)-11,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-al''', is a [[steroid]] [[hormone]]. It is the major [[mineralcorticoid]] and it therefore controls [[electrolyte]] levels, [[blood pressure]] and hydration. Aldosterone is synthesized from [[corticosterone]] by oxidation of the C-18 methyl group to form an aldehyde. | ||
Primary aldosteronism underlies about 10% of cases of resistant [[hypertension]].<ref name="pmid18539224">{{cite journal |author=Douma S, Petidis K, Doumas M, ''et al'' |title=Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study |journal=Lancet |volume=371 |issue=9628 |pages=1921–6 |year=2008 |month=June |pmid=18539224 |doi=10.1016/S0140-6736(08)60834-X |url=http://linkinghub.elsevier.com/retrieve/pii/S0140-6736(08)60834-X |issn=}}</ref> | |||
==References== | |||
<references/> | |||
== External Links == | == External Links == | ||
* {{CZMed}} | * {{CZMed}} | ||
Revision as of 16:58, 19 September 2008
Aldosterone, also called (11ß)-11,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-al, is a steroid hormone. It is the major mineralcorticoid and it therefore controls electrolyte levels, blood pressure and hydration. Aldosterone is synthesized from corticosterone by oxidation of the C-18 methyl group to form an aldehyde.
Primary aldosteronism underlies about 10% of cases of resistant hypertension.[1]
References
- ↑ Douma S, Petidis K, Doumas M, et al (June 2008). "Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study". Lancet 371 (9628): 1921–6. DOI:10.1016/S0140-6736(08)60834-X. PMID 18539224. Research Blogging.
External Links
- The most up-to-date information about Aldosterone and other drugs can be found at the following sites.
- Aldosterone - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Aldosterone - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Aldosterone - Detailed information from DrugBank.