Amifostine: Difference between revisions
Jump to navigation
Jump to search
imported>David E. Volk (new stub with structure) |
imported>David E. Volk mNo edit summary |
||
Line 1: | Line 1: | ||
{{subpages}} | {{subpages}} | ||
{{Chem infobox | {{Chem infobox | ||
|align=right | |align=right |
Latest revision as of 18:08, 20 June 2011
- The content on this page originated on Wikipedia and is yet to be significantly improved. Contributors are invited to replace and add material to make this an original article.
| |||||||
amifostine | |||||||
| |||||||
Uses: | radiation,chemotherapy | ||||||
Properties: | radical scavenger | ||||||
Hazards: | see side effects & drug interactions | ||||||
|
Amifostine is a cytoprotective agent that scavenges reactive oxygen species and other highly reactive free radicals. It is used to reduce the renal toxicity of cisplatin and to reduce the effects of radiation on normal tissue. It is a prodrug that becomes dephosphorylated by alkaline phosphatase into the active thiol form.
The most up-to-date information about Amifostine and other drugs can be found at the following sites.
- Amifostine - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Amifostine - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Amifostine - Detailed information from DrugBank.